SKU: C-1010-5mg
C42H45ClN6O5S2 Solid Powder - Labshops.com
$79.99
  • Targets: PARP
  • Synonym: ABT 737; ABT-737; ABT737
  • Chemical Name/IUPAC:(R)-4-(4-((4'-chloro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((4-((4-(dimethylamino)-1-(phenylthio)butan-2-yl)amino)-3-nitrophenyl)sulfonyl)benzamide

  • Technical Data
  • Product Name: ABT-737
  • Chemical Formula: C42H45ClN6O5S2
  • Moleculer Weight: 813.43
  • CAS#: 852808-04-9
  • Appearance: Solid powder
  • Purity: > 99% by HPLC
  • Solubility: Soluble in DMSO
  • Storage: Room temperature for 6 months, or -20oC for 3 years

  • Description
    ABT-737 is a BH3 mimetic inhibitor of Bcl-xL, Bcl-2 and Bcl-w with EC50 of 78.7 nM, 30.3 nM and 197.8 nM, respectively. ABT-737 has no inhibition observed against Mcl-1, Bcl-B or Bfl-1.