A-1210477

SKU: C-1004-100mg

Quantity (mg):

5mg

Product Options

Quantity

$91.99

Product Name: A-1210477
Catalog#: C-1004
Targets: MCL-1
Synonym: A-1210477; A1210477; A 1210477 Chemical Name/IUPAC:7-(5-((4-(4-(N,N-dimethylsulfamoyl)piperazin-1-yl)phenoxy)methyl)-1,3-dimethyl-1H-pyrazol-4-yl)-1-(2-morpholinoethyl)-3-(3-(naphthalen-1-yloxy)propyl)-1H-indole-2-carboxylic acid
Technical Data

Product Name: A-1210477
Chemical Formula: C46H55N7O7S
Molecular Weight: 850.05
CAS#: 1668553-26-1
Appearance: Solid powder
Purity: > 99% by HPLC
Solubility: Soluble in DMSO
Storage: Room temperature for months, or -20ºC for three years
Description
A-1210477 is a potent and selective MCL-1 inhibitor. A-1210477 disrupted the interaction between MCL-1 and pro-apoptotic BIM, inducing the hallmarks of apoptosis in MCL-1-dependent multiple myeloma and non-small cell lung cancer cell lines.