SKU: C-1004-100mg
C46H55N7O7S solid powder-

  • Product Name: A-1210477
  • Catalog#: C-1004
  • Targets: MCL-1
  • Synonym: A-1210477; A1210477; A 1210477 Chemical Name/IUPAC:7-(5-((4-(4-(N,N-dimethylsulfamoyl)piperazin-1-yl)phenoxy)methyl)-1,3-dimethyl-1H-pyrazol-4-yl)-1-(2-morpholinoethyl)-3-(3-(naphthalen-1-yloxy)propyl)-1H-indole-2-carboxylic acid

  • Technical Data
  • Product Name: A-1210477
  • Chemical Formula: C46H55N7O7S
  • Molecular Weight: 850.05
  • CAS#: 1668553-26-1
  • Appearance: Solid powder
  • Purity: > 99% by HPLC
  • Solubility: Soluble in DMSO
  • Storage: Room temperature for months, or -20ºC for three years

  •  Description
    A-1210477 is a potent and selective MCL-1 inhibitor. A-1210477 disrupted the interaction between MCL-1 and pro-apoptotic BIM, inducing the hallmarks of apoptosis in MCL-1-dependent multiple myeloma and non-small cell lung cancer cell lines.