SKU: C-1376-5mg
  • Catalog#: C-1376
  • Quantity: 5mg
  • Targets: Androgen Receptor (AR)
  • Synonym: MDV3100; MDV 3100; MDV-3100; Enzalutamide
  • Chemical Name/IUPAC:4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide
  • SMILES Code: O=C(NC)C1=CC=C(N(C(N2C3=CC=C(C#N)C(C(F)(F)F)=C3)=S)C(C)(C)C2=O)C=C1F
    Technical Data
  • Product Name: Enzalutamide (MDV-3100)
  • Chemical Formula: C21H16F4N4O2S
  • Molecular Weight: 464.43
  • CAS#: 915087-33-1
  • Purity: > 99% by HPLC
  • Solubility: Soluble in DMSO
  • Storage: Room temperature for months, or -20ºC for 3 years
    Enzalutamide (MDV-3100) is an orally bioavailable, organic, non-steroidal small molecule targeting the androgen receptor (AR) with potential antineoplastic activity. Through a mechanism that is reported to be different from other approved AR antagonists, selective androgen receptor modulator MDV3100 inhibits the activity of prostate cancer cell ARs, which may result in a reduction in prostate cancer cell proliferation and, correspondingly, a reduction in the serum prostate specific antigen (PSA) level.