SKU: C-1279
PS-341 (Bortezomib)
$60.00
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  • Catalog#: C-1279
  • Targets: Proteasome
  • Synonym: PS-341; PS 341; PS341; LDP 341; LDP-341 ;LDP341; MLN341; MLN-341; MLN 341; VELCADE.
  • Chemical Name/IUPAC:((R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid
    Technical Data
  • Product Name: PS-341 (Bortezomib)
  • Chemical Formula: C19H25BN4O4
  • Molecular Weight: 384.24
  • CAS#: 179324-69-7
  • Appearance: Solid powder
  • Purity: > 99% by HPLC
  • Solubility: Soluble in DMSO
  • Storage: Room temperature for months, or -20ºC for 3 years
    Description
    PS-341 (Bortezomib) is a potent inhibitor of proteasome, and PS-341 reversibly inhibits the 26S proteasome, a large protease complex that degrades ubiquinated proteins. By blocking the targeted proteolysis normally performed by the proteasome, PS-341 disrupts various cell signaling pathways, leading to cell cycle arrest, apoptosis, and inhibition of angiogenesis.