SKU: C-1248-5mg
PCI-32765 (Ibrutinib) Chemical Formula: C25H24N6O2 Solid Powder
$49.99
  • Catalog#: C-1248
  • Targets: BTK
  • Synonym: PCI32765; PCI-32765; PCI 32765; Ibrutinib; Imbruvica
  • Chemical Name/IUPAC:(R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one
    Technical Data
  • Product Name: PCI-32765 (Ibrutinib)
  • Chemical Formula: C25H24N6O2
  • Molecular Weight: 440.49
  • CAS#: 936563-96-1
  • Appearance: Solid powder
  • Purity: > 99% by HPLC
  • Solubility: Soluble in DMSO
  • Storage: Room temperature for months, or -20ºC for 3 years
    Description
    PCI-32765 (Ibrutinib) is an orally bioavailable small-molecule inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity. BTK inhibitor PCI-32765 binds to and inhibits BTK activity, preventing B-cell activation and B-cell-mediated signaling and inhibiting the growth of malignant B cells that overexpress BTK.