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Catalog#: C-1248 Quantity: 5mg Targets: BTK Synonym: PCI32765; PCI-32765; PCI 32765; Ibrutinib; Imbruvica Chemical Name/IUPAC:(R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one
Product Name: PCI-32765 (Ibrutinib) Chemical Formula: C25H24N6O2 Molecular Weight: 440.49 CAS#: 936563-96-1 Appearance: Solid powder Purity: > 99% by HPLC Solubility: Soluble in DMSO Storage: Room temperature for months, or -20ºC for 3 years
PCI-32765 (Ibrutinib) is an orally bioavailable small-molecule inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity. BTK inhibitor PCI-32765 binds to and inhibits BTK activity, preventing B-cell activation and B-cell-mediated signaling and inhibiting the growth of malignant B cells that overexpress BTK.