AZD-4547
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- Catalog#: C-1057
- Targets: FGFR
- Synonym: AZD4547; AZD-4547; AZD 4547
Technical Data
- Product Name: AZD-4547
- Chemical Formula: C26H33N5O3
- Moleculer Weight: 463.57
- CAS#: 1035270-39-3 (1394854-62-6)
- Appearance: Solid powder
- Purity: > 99% by HPLC
- Solubility: Soluble in DMSO
- Storage: Room temperature for months, or -20ºC for 3 years
Description
AZD-4547 is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with potential antineoplastic activity. AZD-4547 binds to and inhibits FGFR, which may result in the inhibition of FGFR-related signal transduction pathways, leading to the inhibition of tumor cell proliferation and tumor cell death. FGFR is a receptor tyrosine kinase essential to tumor cellular proliferation, differentiation and survival.