AZD-4547

• Catalog#: C-1057
• Targets: FGFR
• Synonym: AZD4547; AZD-4547; AZD 4547

Technical Data

• Product Name: AZD-4547
• Chemical Formula: C26H33N5O3
• Molecular Weight: 463.57
• CAS#: 1035270-39-3 (1394854-62-6)
• Appearance: Solid powder
• Purity: > 99% by HPLC
• Solubility: Soluble in DMSO
• Storage: Room temperature for months, or -20ºC for three years

Description

AZD-4547 is an orally bioavailable fibroblast growth factor receptor (FGFR) inhibitor with potential antineoplastic activity. AZD-4547 binds to and inhibits FGFR, which may hinder FGFR-related signal transduction pathways, inhibiting tumor cell proliferation and cell death. FGFR is a receptor tyrosine kinase essential to tumor cellular proliferation, differentiation, and survival.