E-7386

SKU: C-1432-5mg

C39H48FN9O4 Molecular Weight: 725.87 Solid Powder

Quantity (mg):

5 mg

Product Options

Quantity

$189.99

Catalog#: C-1432

Quantity: 5mg

Targets: CBP/beta-catenin

Synonym: E-7386; E7386; E 7386

Chemical Name/IUPAC:(6S,9aS)-2-allyl-N-benzyl-8-((6-(3-(4-ethylpiperazin-1-yl)azetidin-1-yl)pyridin-2-yl)methyl)-6-(2-fluoro-4-hydroxybenzyl)-4,7-dioxohexahydro-2H-pyrazino[2,1-c][1,2,4]triazine-1(6H)-carboxamide

SMILES Code: O=C(N([C@](CN1CC2=NC(N3CC(N4CCN(CC)CC4)C3)=CC=C2)([H])N5[C@@H](CC6=CC=C(O)C=C6F)C1=O)N(CC=C)CC5=O)NCC7=CC=CC=C7

Technical Data

Product Name: E-7386

Chemical Formula: C39H48FN9O4

Molecular Weight: 725.87

Appearance: Solid powder

Purity: > 99% by HPLC

Solubility: Soluble in DMSO

Storage: Room temperature for months, or -20ºC for 3 years

Description
E-7386 is a first-in-class orally active CBP/beta-catenin modulator, affects the recruitment of T cells into tumor tissues, leading to the enhancement of anti-PD-1 mAb in Wnt/beta-catenin signaling pathway activating tumor model.

E-7386

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