SKU: C-1415
 C22H23ClN4O7S Molecular Weight: 522.96 Solid Powder
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  • Catalog#: C-1415
  • Targets: VEGFR2
  • Synonym: E7080; E-7080; E 7080; Lenvatinib; Lenvatinib mesylate
  • Chemical Name/IUPAC:4-(3-chloro-4-(3-cyclopropylureido)phenoxy)-7-methoxyquinoline-6-carboxamide mesylate
  • SMILES Code: O=C(C1=C(OC)C=C2N=CC=C(OC3=CC=C(NC(NC4CC4)=O)C(Cl)=C3)C2=C1)N.OS(=O)(C)=O Technical Data
  • Product Name: E-7080 (Lenvatinib Mesylate)
  • Chemical Formula: C22H23ClN4O7S
  • Molecular Weight: 522.96
  • CAS#: 417716-92-8 (Lenvatinib Mesylate)
  • Appearance: Solid powder
  • Purity: > 99% by HPLC
  • Solubility: Soluble in DMSO
  • Storage: Room temperature for months, or -20ºC for 3 years

E-7080 (Lenvatinib Mesylate) is orally available inhibitor of vascular endothelial growth factor receptor 2 (VEGFR2, also known as KDR/FLK-1) tyrosine kinase with potential antineoplastic activity. E-7080 blocks VEGFR2 activation by VEGF, resulting in inhibition of the VEGF receptor signal transduction pathway, decreased vascular endothelial cell migration and proliferation, and vascular endothelial cell apoptosis.