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S-22611

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SKU: C-1405-5mg
S-22611 solid powder
$189.99
  • Catalog#: C-1405
  • Targets: EGFR; HER2; HER4
  • Synonym: S-22611; S22611; S 22611; Epertinib
  • Chemical Name/IUPAC:N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[(Z)-N-[[(3R)-morpholin-3-yl]methoxy]-C-prop-1-ynylcarbonimidoyl]quinazolin-4-amine
  • SMILES Code: CC#CC(=NOCC1COCCN1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl
  • Technical Data
  • Product Name: S-22611
  • Chemical Formula:
  • Molecular Weight: 560.03
  • CAS#: 908305-13-5
  • Solubility: Soluble in DMSO
  • Storage: Room temperature for months, or -20ºC for 3 years
    Description
    S-22611 (Epertinib) is a potent, oral, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4, with IC50s of 1.48 nM, 7.15 nM and 2.49 nM, respectively; S-22611 (Epertinib) shows potent antitumor activity.


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