S-22611

SKU: C-1405-5mg

Quantity (mg):

5 mg

Product Options

Quantity

$189.99

Catalog#: C-1405

Targets: EGFR; HER2; HER4

Synonym: S-22611; S22611; S 22611; Epertinib

Chemical Name/IUPAC:N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[(Z)-N-[[(3R)-morpholin-3-yl]methoxy]-C-prop-1-ynylcarbonimidoyl]quinazolin-4-amine

SMILES Code: CC#CC(=NOCC1COCCN1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl

Technical Data

Product Name: S-22611

Chemical Formula:

Molecular Weight: 560.03

CAS#: 908305-13-5

Solubility: Soluble in DMSO

Storage: Room temperature for months, or -20ºC for 3 years

Description
S-22611 (Epertinib) is a potent, oral, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4, with IC50s of 1.48 nM, 7.15 nM and 2.49 nM, respectively; S-22611 (Epertinib) shows potent antitumor activity.

S-22611

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