Targets: PI3K; EGFR
Synonym: MTX-211; MTX211; MTX 211
Product Name: MTX-211
Molecular Weight: 478.32
Purity: > 99% by HPLC
Solubility: Soluble in DMSO
Storage: Room temperature for months, or -20ºC for 3 years
MTX-211 is a first-in-class dual inhibitor of PI3K and EGFR kinases with demonstrated in vivo anticancer activity against multiple KRAS mutant colorectal tumors. MTX-211 is highly selective for EGFR and PI3K family members.