Home / Collections / CHEMICALS / GSK-2830371

GSK-2830371

-
SKU: C-1372-5mg
GSK-2830371 Chemical Formula: C23H29ClN4O2S Solid Powder
$103.99
  • Catalog#: C-1372
  • Targets: Wip1
  • Synonym: GSK-2830371 ; GSK2830371 ; GSK 2830371
    Technical Data
  • Product Name: GSK-2830371
  • Chemical Formula: C23H29ClN4O2S
  • Molecular Weight: 461.02
  • CAS#: 1404456-53-6
  • Purity: > 99% by HPLC
  • Solubility: Soluble in DMSO
  • Storage: Room temperature for months, or -20ºC for 3 years
    Description
    GSK-2830371 is a potent and selective allosteric inhibitor of Wip1 phosphatase (IC50 = 6 nM). GSK-2830371 exhibits selectivity for Wip1 over 21 other phosphatases. Increases phosphorylation of Wip1 substrates, including p53, Chk2, H2AX and ATM. Attenuates tumor cell growth in a variety of lymphoid cell lines. Also, GSK-2830371 inhibits lymphoma xenograft growth in vivo.


    • Related products

    C26H26F6N4O3 BMS-906024 Solid powder

    -

    BMS-906024

    from $228.99

    C47H55ClF3N5O6S3 Solid Powder - Labshops.com

    -

    ABT-263 (Navitoclax)

    from $57.99

    MEK-162 (ARRY-162) solid powder

    -

    MEK-162 (ARRY-162)

    from $68.99

    C32H37N5O6 Solid Powder

    -

    E-7090

    from $325.99