Synonym: VE822; VE-822; VE 822; VX970; VX-970; VX 970
Chemical Name/IUPAC:5-(4-(isopropylsulfonyl)phenyl)-3-(3-(4-((methylamino)methyl)phenyl)isoxazol-5-yl)pyrazin-2-amineTechnical Data
Product Name: VE-822 (VX-970)
Chemical Formula: C24H25N5O3S
Molecular Weight: 463.55
CAS#: 1232416-25-9
Purity: > 99% by HPLC
Solubility: Soluble in DMSO
Storage: Room temperature for months, or -20ºC for 3 yearsDescription VE-822 (VX-970) is a potent ATR inhibitor. VE-822 decreased maintenance of cell-cycle checkpoints, increased persistent DNA damage and decreased homologous recombination in irradiated cancer cells.