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TL-32711 (Birinapant)

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SKU: C-1318-5mg
TL-32711 (Birinapant) Chemical Formula: C42H56F2N8O6
$79.99
  • Catalog#: C-1318
  • Targets: SMAC
  • Synonym: TL32711; TL-32711; TL 32711; SMAC mimetic; Birinapant
  • Chemical Name/IUPAC:(2S)-N-[(2S)-1-[(2R,4S)-2-[[6-fluoro-2-[6-fluoro-3-[[(2R,4S)-4-hydroxy-1-[(2S)-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]pyrrolidin-2-yl]methyl]-1H-indol-2-yl]-1H-indol-3-yl]methyl]-4-hydroxypyrrolidin-1-yl]-1-oxobutan-2-yl]-2-(methylamino)propanamide
    Technical Data
  • Product Name: TL-32711 (Birinapant)
  • Chemical Formula: C42H56F2N8O6
  • Molecular Weight: 806.94
  • CAS#: 1260251-31-7
  • Purity: > 99% by HPLC
  • Solubility: Soluble in DMSO
  • Storage: Room temperature for months, or -20ºC for 3 years
    Description
    TL-32711 (Birinapant) is a synthetic small molecule and peptido mimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor of IAP (Inhibitor of Apoptosis Protein) family proteins, with potential antineoplastic activity. As a SMAC mimetic and IAP antagonist, TL32711 binds to and inhibits the activity of IAPs, such as X chromosome-linked IAP (XIAP) and cellular IAPs 1 and 2.


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