Synonym: TL32711; TL-32711; TL 32711; SMAC mimetic; Birinapant
Product Name: TL-32711 (Birinapant)
Chemical Formula: C42H56F2N8O6
Molecular Weight: 806.94
Purity: > 99% by HPLC
Solubility: Soluble in DMSO
Storage: Room temperature for months, or -20ºC for 3 years
TL-32711 (Birinapant) is a synthetic small molecule and peptido mimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor of IAP (Inhibitor of Apoptosis Protein) family proteins, with potential antineoplastic activity. As a SMAC mimetic and IAP antagonist, TL32711 binds to and inhibits the activity of IAPs, such as X chromosome-linked IAP (XIAP) and cellular IAPs 1 and 2.