Rocaglamide
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Technical Data
Description
Rocaglamide is an immunosuppressant, and a potent inhibitor of NF-?B activation in T cells, with an almost complete inhibition at 200nM. Suppresses cytokine production (IFN-?, TNF-?, IL-2 and IL-4) and inhibits NF-AT in peripheral blood T cells at concentrations that do not impair NF-?B and AP-1 activities.