SKU: C-1290-5mg
  • Catalog#: C-1290
  • Targets: RAF
  • Synonym: RO5126766; RO 5126766; RO5126766; CH5126766; CH5126766; CH 5126766
  • Chemical Name/IUPAC:3-[[2-[(Methylaminosulfonyl)amino]-3-fluoropyridin-4-yl]methyl]-4-methyl-7-[(pyrimidin-2-yl)oxy]-2H-1-benzopyran-2-one
    Technical Data
  • Product Name: RO-5126766
  • Chemical Formula: C21H18FN5O5S
  • Molecular Weight: 471.46
  • CAS#: 946128-88-7
  • Appearance: Solid powder
  • Purity: > 99% by HPLC
  • Solubility: Soluble in DMSO
  • Storage: Room temperature for months, or -20ºC for 3 years
    RO-5126766 is a dual Raf and MEK inhibitor with potential anti-neoplastic activity. Raf/MEK dual kinase Inhibitor RO5126766 specifically inhibits the kinase activities of Raf and MEK, resulting in the inhibition of of target gene transcription that promotes malignant transformation of cells.