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Catalog#: C-1287 Quantity: 5mg Targets: MDM2 Synonym: RG7388; RG 7388; RG-7388; RO5503781; RO-5503781; RO 5503781; Idasanutlin Chemical Name/IUPAC:4-((2R,3S,4R,5S)-3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-neopentylpyrrolidine-2-carboxamido)-3-methoxybenzoic acid
Product Name: RG-7388 (Idasanutlin) Chemical Formula: C31H29Cl2F2N3O4 Molecular Weight: 616.48 CAS#: 1229705-06-9 Appearance: Solid powder Purity: > 99% by HPLC Solubility: Soluble in DMSO Storage: Room temperature for months, or -20ºC for 3 years
RG-7388 (Idasanutlin) is a highly potent and selective MDM2 antagonist with potential anticancer activity. RG-7388 binds to MDM2 blocking the interaction between the MDM2 protein and the transcriptional activation domain of the tumor suppressor protein p53.