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MK-4827 (Niraparib)

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SKU: C-1225-5mg
MK-4827 (Niraparib) Chemical Formula: C19H20N4O Solid Powder
$103.99
  • Catalog#: C-1225
  • Targets: PARP
  • Synonym: MK-4827; MK-4827; MK4827; Niraparib. Niraparib free base
  • Chemical Name/IUPAC:(S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide
    Technical Data
  • Product Name: MK-4827 (Niraparib)
  • Chemical Formula: C19H20N4O
  • Molecular Weight: 320.39
  • CAS#: 1038915-60-4 (free base)
  • Appearance: Solid powder
  • Purity: > 99% by HPLC
  • Solubility: Soluble in DMSO
  • Storage: Room temperature for months, or -20ºC for 3 years
    Description
    MK-4827 (Niraparib) is an inhibitor of poly (ADP-ribose) polymerase (PARP) with potential antineoplastic activity. MK-4827 inhibits PARP activity, enhancing the accumulation of DNA strand breaks and promoting genomic instability and apoptosis.


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