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Catalog#: C-1225 Quantity: 5mg Targets: PARP Synonym: MK-4827; MK-4827; MK4827; Niraparib. Niraparib free base Chemical Name/IUPAC:(S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide
Product Name: MK-4827 (Niraparib) Chemical Formula: C19H20N4O Molecular Weight: 320.39 CAS#: 1038915-60-4 (free base) Appearance: Solid powder Purity: > 99% by HPLC Solubility: Soluble in DMSO Storage: Room temperature for months, or -20ºC for 3 years
MK-4827 (Niraparib) is an inhibitor of poly (ADP-ribose) polymerase (PARP) with potential antineoplastic activity. MK-4827 inhibits PARP activity, enhancing the accumulation of DNA strand breaks and promoting genomic instability and apoptosis.