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Catalog#: C-1220 Quantity: 5mg Targets: KSP Synonym: MK0731, MK-0731, MK 0731 Chemical Name/IUPAC:(S)-4-(2,5-difluorophenyl)-N-((3R,4S)-3-fluoro-1-methylpiperidin-4-yl)-2-(hydroxymethyl)-N-methyl-2-phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide
Product Name: MK-0731 Chemical Formula: C25H28F3N3O2 Molecular Weight: 459.5 CAS#: 845256-65-7 Appearance: Solid powder Purity: > 99% by HPLC Solubility: Soluble in DMSO Storage: Room temperature for months, or -20ºC for 3 years
MK-0731 is a potent and selective inhibitor of kinesin spindle protein (KSP), which may result in the inhibition of mitotic spindle assembly, induction of cell cycle arrest during the mitotic phase, and apoptosis in tumor cells that overexpress KSP.