SKU: C-1220-5mg
MK-0731 Chemical Formula: C25H28F3N3O2 Solid Powder
  • Catalog#: C-1220
  • Targets: KSP
  • Synonym: MK0731, MK-0731, MK 0731
  • Chemical Name/IUPAC:(S)-4-(2,5-difluorophenyl)-N-((3R,4S)-3-fluoro-1-methylpiperidin-4-yl)-2-(hydroxymethyl)-N-methyl-2-phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide
    Technical Data
  • Product Name: MK-0731
  • Chemical Formula: C25H28F3N3O2
  • Molecular Weight: 459.5
  • CAS#: 845256-65-7
  • Appearance: Solid powder
  • Purity: > 99% by HPLC
  • Solubility: Soluble in DMSO
  • Storage: Room temperature for months, or -20ºC for 3 years
    MK-0731 is a potent and selective inhibitor of kinesin spindle protein (KSP), which may result in the inhibition of mitotic spindle assembly, induction of cell cycle arrest during the mitotic phase, and apoptosis in tumor cells that overexpress KSP.