MGCD-516 (Sitravatinib)

SKU: C-1217-5mg

Quantity (mg):

5 mg

Product Options

Quantity

$91.99

Catalog#: C-1217

Targets: RTKs

Synonym: MGCD516; MGCD-516; MGCD 516; MG516; MG 516; MG-516; Sitravatinib

Chemical Name/IUPAC:N-(3-fluoro-4-((2-(5-(((2-methoxyethyl)amino)methyl)pyridin-2-yl)thieno[3,2-b]pyridin-7-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide

Technical Data

Product Name: MGCD-516 (Sitravatinib)

Chemical Formula: C33H29F2N5O4S

Molecular Weight: 629.68

CAS#: 1123837-84-2

Appearance: Solid powder

Purity: > 99% by HPLC

Solubility: Soluble in DMSO

Storage: Room temperature for months, or -20ºC for 3 years

Description
MGCD-516 (Sitravatinib) is a novel small molecule inhibitor targeting multiple RTKs involved in driving sarcoma cell growth. MGCD-516 treatment resulted in significant blockade of phosphorylation of potential driver RTKs and induced potent anti-proliferative effects in vitro. MGCD-516 treatment of tumor xenografts in vivo resulted in significant suppression of tumor growth.

MGCD-516 (Sitravatinib)

Related products

A-1210477

ABT-199 (Venectoclax)

ABT-263 (Navitoclax)

ABT-737