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Catalog#: C-1216 Quantity: 5mg Targets: c-Met Synonym: MGCD-265; MGCD 265; MGCD265; Glesatinib Chemical Name/IUPAC:N-((3-fluoro-4-((2-(5-(((2-methoxyethyl)amino)methyl)pyridin-2-yl)thieno[3,2-b]pyridin-7-yl)oxy)phenyl)carbamothioyl)-2-(4-fluorophenyl)acetamide
Product Name: MGCD-265 (Glesatinib) Chemical Formula: C31H27F2N5O3S2 Molecular Weight: 619.7 CAS#: 936694-12-1 Appearance: Solid powder Purity: > 99% by HPLC Solubility: Soluble in DMSO Storage: Room temperature for months, or -20ºC for 3 years
MGCD-265 (Glesatinib) is an orally bioavailable, small-molecule, multitargeted tyrosine kinase inhibitor with potential antineoplastic activity. MGCD-265 binds to and inhibits the phosphorylation of several receptor tyrosine kinases (RTKs), including the c-Met receptor (hepatocyte growth factor receptor); the Tek/Tie-2 receptor; vascular endothelial growth factor receptor (VEGFR) types 1, 2, and 3; and the macrophage-stimulating 1 receptor (MST1R or RON).