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MGCD-265 (Glesatinib)

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SKU: C-1216-5mg
MGCD-265 (Glesatinib) Chemical Formula: C31H27F2N5O3S2 Solid Powder
$91.99
  • Catalog#: C-1216
  • Targets: c-Met
  • Synonym: MGCD-265; MGCD 265; MGCD265; Glesatinib
  • Chemical Name/IUPAC:N-((3-fluoro-4-((2-(5-(((2-methoxyethyl)amino)methyl)pyridin-2-yl)thieno[3,2-b]pyridin-7-yl)oxy)phenyl)carbamothioyl)-2-(4-fluorophenyl)acetamide
    Technical Data
  • Product Name: MGCD-265 (Glesatinib)
  • Chemical Formula: C31H27F2N5O3S2
  • Molecular Weight: 619.7
  • CAS#: 936694-12-1
  • Appearance: Solid powder
  • Purity: > 99% by HPLC
  • Solubility: Soluble in DMSO
  • Storage: Room temperature for months, or -20ºC for 3 years
    Description
    MGCD-265 (Glesatinib) is an orally bioavailable, small-molecule, multitargeted tyrosine kinase inhibitor with potential antineoplastic activity. MGCD-265 binds to and inhibits the phosphorylation of several receptor tyrosine kinases (RTKs), including the c-Met receptor (hepatocyte growth factor receptor); the Tek/Tie-2 receptor; vascular endothelial growth factor receptor (VEGFR) types 1, 2, and 3; and the macrophage-stimulating 1 receptor (MST1R or RON).


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