LOXO-101 (ARRY-470)

SKU: C-1200-5mg

Quantity (mg):

5 mg

Product Options

Quantity

$91.99

Catalog#: C-1200

Targets: TRK

Synonym: LOXO 101; LOXO-101; LOXO101; ARRY-470; ARRY470; ARRY 470; larotrectinib

Chemical Name/IUPAC:(S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide

Technical Data

Product Name: LOXO-101 (ARRY-470)

Chemical Formula: C21H22F2N6O2

Molecular Weight: 428.44

CAS#: 1223403-58-4

Appearance: Solid powder

Purity: > 99% by HPLC

Solubility: Soluble in DMSO

Storage: Room temperature for months, or -20ºC for 3 years

Description
LOXO-101 (ARRY-470) is an orally bioavailable, potent, ATP-competitive inhibitor of TRKA, TRKB, and TRKC.