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Catalog#: C-1200 Quantity: 5mg Targets: TRK Synonym: LOXO 101; LOXO-101; LOXO101; ARRY-470; ARRY470; ARRY 470; larotrectinib Chemical Name/IUPAC:(S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide
Product Name: LOXO-101 (ARRY-470) Chemical Formula: C21H22F2N6O2 Molecular Weight: 428.44 CAS#: 1223403-58-4 Appearance: Solid powder Purity: > 99% by HPLC Solubility: Soluble in DMSO Storage: Room temperature for months, or -20ºC for 3 years
LOXO-101 (ARRY-470) is an orally bioavailable, potent, ATP-competitive inhibitor of TRKA, TRKB, and TRKC.