LCL-161
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Technical Data
Description
LCL-161 is a n orally bioavailable second mitochondrial-derived activator of caspases (SMAC) mimetic and inhibitor of IAP (Inhibitor of Apoptosis Protein) family of proteins, with potential antineoplastic activity. SMAC mimetic LCL-161 binds to IAPs, such as X chromosome-linked IAP (XIAP) and cellular IAPs 1 and 2.