LCL-161

SKU: C-1196-5mg

Quantity (mg):

5 mg

Product Options

Quantity

$103.99

Catalog#: C-1196

Targets: SMAC

Synonym: LCL161; LCL 161; LCL-161

Chemical Name/IUPAC:(S)-N-((S)-1-cyclohexyl-2-((S)-2-(4-(4-fluorobenzoyl)thiazol-2-yl)pyrrolidin-1-yl)-2-oxoethyl)-2-(methylamino)propanamide

Technical Data

Product Name: LCL-161

Chemical Formula: C26H33FN4O3S

Molecular Weight: 500.63

CAS#: 1005342-46-0

Appearance: Solid powder

Purity: > 99% by HPLC

Solubility: Soluble in DMSO

Storage: Room temperature for months, or -20ºC for 3 years

Description
LCL-161 is a n orally bioavailable second mitochondrial-derived activator of caspases (SMAC) mimetic and inhibitor of IAP (Inhibitor of Apoptosis Protein) family of proteins, with potential antineoplastic activity. SMAC mimetic LCL-161 binds to IAPs, such as X chromosome-linked IAP (XIAP) and cellular IAPs 1 and 2.

LCL-161

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