LBH-589 (Panobinostat)

SKU: C-1195

Made in USA, High-Purity Standard Quality

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Catalog#: C-1195

Quantity: 5mg

Targets: HDAC

Synonym: LBH589; LBH 589; LBH-589; NVP-LBH589; NVP-LBH 589; Panobinostat; Farydak

Chemical Name/IUPAC:(2E)-N-hydroxy-3-[4-({[2-(2-methyl-1H-indol-3-yl)ethyl]amino}methyl)phenyl]acrylamide

Technical Data

Product Name: LBH-589 (Panobinostat)

Chemical Formula: C21H23N3O2

Molecular Weight: 349.43

CAS#: 404950-80-7

Appearance: Solid powder

Purity: > 99% by HPLC

Solubility: Soluble in DMSO

Storage: Room temperature for months, or -20ºC for 3 years

Description
LBH-589 (Panobinostat) is a cinnamic hydroxamic acid analogue with potential antineoplastic activity. Panobinostat selectively inhibits histone deacetylase (HDAC), inducing hyperacetylation of core histone proteins, which may result in modulation of cell cycle protein expression, cell cycle arrest in the G2/M phase and apoptosis.

LBH-589 (Panobinostat)

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