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LBH-589 (Panobinostat)

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SKU: C-1195-5mg
LBH-589 (Panobinostat) Chemical Formula: C21H23N3O2 Solid Powder
$39.99
  • Catalog#: C-1195
  • Targets: HDAC
  • Synonym: LBH589; LBH 589; LBH-589; NVP-LBH589; NVP-LBH 589; Panobinostat; Farydak
  • Chemical Name/IUPAC:(2E)-N-hydroxy-3-[4-({[2-(2-methyl-1H-indol-3-yl)ethyl]amino}methyl)phenyl]acrylamide
    Technical Data
  • Product Name: LBH-589 (Panobinostat)
  • Chemical Formula: C21H23N3O2
  • Molecular Weight: 349.43
  • CAS#: 404950-80-7
  • Appearance: Solid powder
  • Purity: > 99% by HPLC
  • Solubility: Soluble in DMSO
  • Storage: Room temperature for months, or -20ºC for 3 years
    Description
    LBH-589 (Panobinostat) is a cinnamic hydroxamic acid analogue with potential antineoplastic activity. Panobinostat selectively inhibits histone deacetylase (HDAC), inducing hyperacetylation of core histone proteins, which may result in modulation of cell cycle protein expression, cell cycle arrest in the G2/M phase and apoptosis.


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