Made in USA, High-Purity Standard Quality We offer a low price guarantee to ensure that you always get your penny's worth. If you find a lower price on an identical item within 7 days of your purchase from another US competitor, contact us and we'll price match! Same day FREE shipping, if the item is in stock!
Catalog#: C-1183 Quantity: 5mg Targets: mTOR Synonym: INK128; INK-128; INK 128; MLN0128; MLN 0128; MLN-0128; Sapanisertib Chemical Name/IUPAC:3-(2-amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Product Name: INK-128 (Sapanisertib) Chemical Formula: C15H15N7O Molecular Weight: 309.33 CAS#: 1224844-38-5 Appearance: Solid powder Purity: > 99% by HPLC Solubility: Soluble in DMSO Storage: Room temperature for months, or -20ºC for 3 years
INK-128 (Sapanisertib) is an orally bioavailable inhibitor of raptor-mTOR (TOR complex 1 or TORC1) and rictor-mTOR (TOR complex 2 or TORC2) with potential antineoplastic activity. TORC1/2 inhibitor INK128 binds to and inhibits both TORC1 and TORC2 complexes of mTOR, which may result in tumor cell apoptosis and a decrease in tumor cell proliferation. TORC1 and 2 are upregulated in some tumors and play an important role in the PI3K/Akt/mTOR signaling pathway, which is frequently dysregulated in human cancers.