SKU: C-1149-5mg
GDC-0980 (Apitolisib) Chemical Formula: C23H30N8O3S
  • Catalog#: C-1149
  • Targets: PI3K
  • Synonym: GDC0980; GDC-0980; GDC 0980; RG7422; RG-7422; RG 7422; GNE 390; GNE-390; GNE390; Apitolisib
  • Chemical Name/IUPAC:(S)-1-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)piperazin-1-yl)-2-hydroxypropan-1-one
    Technical Data
  • Product Name: GDC-0980 (Apitolisib)
  • Chemical Formula: C23H30N8O3S
  • Molecular Weight: 498.6
  • CAS#: 1032754-93-0
  • Appearance: Solid powder
  • Purity: > 99% by HPLC
  • Solubility: Soluble in DMSO
  • Storage: Room temperature for months, or -20ºC for 3 years
    GDC-0980 (Apitolisib) is a potent dual PI3 kinase/mTOR inhibitor. GDC-0980 inhibits both PI3K kinase and mTOR kinase, which may result in tumor cell apoptosis and growth inhibition of cancer cells overexpressing PI3K/mTOR.