GDC-0449 (Vismodegib)

SKU: C-1143-5mg

Quantity (mg):

5 mg

Product Options

Quantity

$45.99

Catalog#: C-1143

Targets: Hedgehog

Synonym: GDC0449; GDC 0449; GDC-0449; RG3616; RG 3616; RG-3616. Vismodegib; Erivedge

Chemical Name/IUPAC:2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide

Technical Data

Product Name: GDC-0449 (Vismodegib)

Chemical Formula: C19H14Cl2N2O3S

Molecular Weight: 421.3

CAS#: 879085-55-9

Appearance: Solid powder

Purity: > 99% by HPLC

Solubility: Soluble in DMSO

Storage: Room temperature for months, or -20ºC for 3 years

Description
GDC-0449 (Vismodegib) is a potent, orally bioavailable hedgehog antagonist with antineoplastic activity. GDC-0449 targets the Hedgehog signaling pathway, blocking the activities of the Hedgehog-ligand cell surface receptors PTCH and/or SMO and suppressing Hedgehog signaling.

GDC-0449 (Vismodegib)

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