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GDC-0084

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SKU: C-1141
GDC-0084 Chemical Formula: C18H22N8O2 Solid Water
$120.00
  • Made in USA, High-Purity Standard Quality
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  • Catalog#: C-1141
  • Quantity: 5mg
  • Targets: PI3K
  • Synonym: RG7666; RG-7666; RG 7666; GDC-0084; GDC0084; GDC 0084
  • Chemical Name/IUPAC:5-(6,6-dimethyl-4-morpholino-8,9-dihydro-6H-[1,4]oxazino[4,3-e]purin-2-yl)pyrimidin-2-amine
    Technical Data
  • Product Name: GDC-0084
  • Chemical Formula: C18H22N8O2
  • Molecular Weight: 382.42
  • CAS#: 1382979-44-3
  • Appearance: Solid powder
  • Purity: > 99% by HPLC
  • Solubility: Soluble in DMSO
  • Storage: Room temperature for months, or -20ºC for 3 years
    Description
    GDC-0084 is a potent PI3K inhibitor with antineoplastic activity. GDC-0084 specifically inhibits PI3K in the PI3K/AKT kinase (or protein kinase B) signaling pathway, thereby inhibiting the activation of the PI3K signaling pathway. This may result in the inhibition of both cell growth and survival in susceptible tumor cell populations. Activation of the PI3K signaling pathway is frequently associated with tumorigenesis.


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