GDC-0084

SKU: C-1141

Made in USA, High-Purity Standard Quality

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Catalog#: C-1141

Quantity: 5mg

Targets: PI3K

Synonym: RG7666; RG-7666; RG 7666; GDC-0084; GDC0084; GDC 0084

Chemical Name/IUPAC:5-(6,6-dimethyl-4-morpholino-8,9-dihydro-6H-[1,4]oxazino[4,3-e]purin-2-yl)pyrimidin-2-amine

Technical Data

Product Name: GDC-0084

Chemical Formula: C18H22N8O2

Molecular Weight: 382.42

CAS#: 1382979-44-3

Appearance: Solid powder

Purity: > 99% by HPLC

Solubility: Soluble in DMSO

Storage: Room temperature for months, or -20ºC for 3 years

Description
GDC-0084 is a potent PI3K inhibitor with antineoplastic activity. GDC-0084 specifically inhibits PI3K in the PI3K/AKT kinase (or protein kinase B) signaling pathway, thereby inhibiting the activation of the PI3K signaling pathway. This may result in the inhibition of both cell growth and survival in susceptible tumor cell populations. Activation of the PI3K signaling pathway is frequently associated with tumorigenesis.

GDC-0084

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