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Catalog#: C-1111 Targets: FLT3 Synonym: CP 868596; CP868596; CP-868596; ARO 002; RO-002; RO002; Crenolanib Chemical Name/IUPAC:1-(2-(5-((3-methyloxetan-3-yl)methoxy)-1H-benzo[d]imidazol-1-yl)quinolin-8-yl)piperidin-4-amine
Product Name: CP-868596 (Crenolanib) Chemical Formula: C26H29N5O2 Molecular Weight: 443.54 CAS#: 670220-88-9 Appearance: Solid powder Purity: > 99% by HPLC Solubility: Soluble in DMSO Storage: Room temperature for months, or -20ºC for 3 years
CP-868596 (Crenolanib) is an orally bioavailable small molecule, targeting the platelet-derived growth factor receptor (PDGFR) with potential antineoplastic activity. CP-868596 also potently inhibits FLT3, sensitive to D842V mutation not V561D mutation.