CH-5132799

SKU: C-1107

Made in USA, High-Purity Standard Quality

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Catalog#: C-1107

Targets: PI3K

Synonym: CH5132799; CH-5132799; CH 5132799; PA-799; PA799; PA-799

Chemical Name/IUPAC:5-(7-(methylsulfonyl)-2-morpholino-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrimidin-2-amine

Technical Data

Product Name: CH-5132799

Chemical Formula: C15H19N7O3S

Molecular Weight: 377.42

CAS#: 1007207-67-1

Appearance: Solid powder

Purity: > 99% by HPLC

Solubility: Soluble in DMSO

Storage: Room temperature for months, or -20ºC for 3 years

Description
CH5132799 is a potent, orally available class I PI3K inhibitor, which exhibited a strong inhibitory activity especially against PI3K? (IC(50)=0.014 ?M). Tumors harboring PIK3CA mutations were significantly sensitive to CH-5132799 in vitro and were remarkably regressed by CH-5132799 in in vivo mouse xenograft models.

CH-5132799

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