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CH-5132799

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SKU: C-1107
CH-5132799 Chemical Formula: C15H19N7O3S Solid Powder
$150.00
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  • Catalog#: C-1107
  • Targets: PI3K
  • Synonym: CH5132799; CH-5132799; CH 5132799; PA-799; PA799; PA-799
  • Chemical Name/IUPAC:5-(7-(methylsulfonyl)-2-morpholino-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrimidin-2-amine
    Technical Data
  • Product Name: CH-5132799
  • Chemical Formula: C15H19N7O3S
  • Molecular Weight: 377.42
  • CAS#: 1007207-67-1
  • Appearance: Solid powder
  • Purity: > 99% by HPLC
  • Solubility: Soluble in DMSO
  • Storage: Room temperature for months, or -20ºC for 3 years
    Description
    CH5132799 is a potent, orally available class I PI3K inhibitor, which exhibited a strong inhibitory activity especially against PI3K? (IC(50)=0.014 ?M). Tumors harboring PIK3CA mutations were significantly sensitive to CH-5132799 in vitro and were remarkably regressed by CH-5132799 in in vivo mouse xenograft models.


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