CB-5083

SKU: C-1097-5mg

Quantity (mg):

5 mg

Product Options

Quantity

$116.99

Catalog#: C-1097

Targets: p97

Synonym: CB5083; CB-5083; CB 5083

Chemical Name/IUPAC:1-(4-(benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl)-2-methyl-1H-indole-4-carboxamide

Technical Data

Product Name: CB-5083

Chemical Formula: C24H23N5O2

Molecular Weight: 413.4

CAS#: 1542705-92-9

Appearance: Solid powder

Purity: > 99% by HPLC

Solubility: Soluble in DMSO

Storage: Room temperature for months, or -20ºC for 3 years

Description
CB-5083 is a novel first in class, potent orally bio-available p97 inhibitor that disrupts cellular protein homeostasis and demonstrates anti-tumor activity in solid and hematological models . CB-5083 causes rapid and sustained accumulation of poly-ubiquitin in tumor xenografts after a single administration.

CB-5083

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