SKU: C-1079-10mg
C26H31Cl2N7O3 BGJ-398
  • Catalog#: C-1079
  • Targets: FGFR
  • Synonym: NVPBGJ398; NVPBGJ 398; NVPBGJ-398; BGJ398; BGJ-398; BG J398; Infigratinib
    Technical Data
  • Product Name: BGJ-398
  • Chemical Formula: C26H31Cl2N7O3
  • Molecular Weight: 560.47
  • CAS#: 872511-34-7 (free base)
  • Appearance: Solid powder
  • Purity: > 99% by HPLC
  • Solubility: Soluble in DMSO
  • Storage: Room temperature for months, or -20ºC for 3 years
    BGJ-398 is a pan FGFR kinase inhibitor, and is an orally bioavailable pan inhibitor of human fibroblast growth factor receptors (FGFRs) with potential antiangiogenic and antineoplastic activities. pan FGFR kinase inhibitor BGJ-398 selectively binds to and inhibits the activities of FGFRs, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation, and the induction of tumor cell death.