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Catalog#: C-1075 Quantity: 5mg Targets: VEGFR Synonym: BAY-73-4506; BAY 73-4506, BAY 734506; BAY734506; BAY-734506; Regorafenib. trade name: Stivarga.
Product Name: Regorafenib (BAY-73-4506) Chemical Formula: C21H15ClF4N4O3 Moleculer Weight: 482.81 CAS#: 755037-03-7 Appearance: Solid powder Purity: > 99% by HPLC Solubility: Soluble in DMSO Storage: Room temperature for months, or -20ºC for 3 years
Regorafenib (BAY 73-4506) is a n orally bioavailable small molecule with potential antiangiogenic and antineoplastic activities. Regorafenib binds to and inhibits vascular endothelial growth factor receptors (VEGFRs) 2 and 3, and Ret, Kit, PDGFR and Raf kinases, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation.