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Catalog#: C-1070 Targets: PI3K?/? Synonym: BAY-1082439; BAY1082439; BAY 1082439
Product Name: BAY-1082439 Chemical Formula: C25H30N6O5 Moleculer Weight: 494.55 CAS#: 1375469-38-7 Appearance: Solid powder Purity: > 99% by HPLC Solubility: Soluble in DMSO Storage: Room temperature for months, or -20ºC for 3 years
BAY-1082439 is an orally bioavailable inhibitor of the class I phosphoinositide 3-kinase (PI3K) alpha and beta isoforms with potential antineoplastic activity. BAY-1082439 selectively inhibits both PI3K alpha, including mutated forms of PIK3CA, and PI3K beta in the PI3K/Akt/mTOR pathway, which may result in tumor cell apoptosis and growth inhibition in PI3K-expressing and/or PTEN-driven tumor cells.