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Catalog#: C-1062 Targets: MEK Synonym: AZD6244; AZD-6244; AZD 6244; ARRY142886; ARRY 142886; ARRY-142886; ARRY886; ARRY-886; ARRY 886 ; selumetinib
Product Name: AZD-6244 (Selumetinib) Chemical Formula: C17H15BrClFN4O3 Moleculer Weight: 457.68 CAS#: 606143-52-6 Appearance: Solid powder Purity: > 99% by HPLC Solubility: Soluble in DMSO Storage: Room temperature for months, or -20ºC for 3 years
AZD-6244 (Selumetinib) is an orally bioavailable small molecule with potential antineoplastic activity. AZD-6244inhibits mitogen-activated protein kinase kinases (MEK or MAPK/ERK kinases) 1 and 2, which may prevent the activation of MEK1/2-dependent effector proteins and transcription factors, and so may inhibit cellular proliferation in MEK-overexpressing tumor cells.