SKU: C-1058-5mg
AZD-5363 Chemical Formula: C21H25ClN6O2 Moleculer Weight: 428.91 CAS#: 1143532-39-1 Appearance: Solid powder Purity: > 99% by HPLC Solubility: Soluble in DMSO
$79.99

  • Catalog#: C-1058
  • Targets: AKT
  • Synonym: AZD5363; AZD-5363; AZD 5363

Technical Data

  • Product Name: AZD-5363
  • Chemical Formula: C21H25ClN6O2
  • Moleculer Weight: 428.91
  • CAS#: 1143532-39-1
  • Appearance: Solid powder
  • Purity: > 99% by HPLC
  • Solubility: Soluble in DMSO
  • Storage: Room temperature for months, or -20ºC for 3 years

Description


AZD-5363 is an orally available inhibitor of the serine/threonine protein kinase AKT (protein kinase B) with potential antineoplastic activity. AZD-5363 binds to and inhibits all AKT isoforms. Inhibition of AKT prevents the phosphorylation of AKT substrates that mediate cellular processes, such as cell division, apoptosis, and glucose and fatty acid metabolism.