AZD-2014 (Vistusertib)
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- Catalog#: C-1050
- Targets: mTOR
- Synonym: AZD2014; AZD-2014; AZD 2014; Vistusertib
Technical Data
- Product Name: AZD-2014 (Vistusertib)
- Chemical Formula: C25H30N6O3
- Moleculer Weight: 462.54
- CAS#: 1009298-59-2
- Appearance: Solid powder
- Purity: > 99% by HPLC
- Solubility: Soluble in DMSO
- Storage: Room temperature for months, or -20ºC for 3 years
Description
AZD-2014 (Vistusertib) is an orally bioavailable inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity. AZD-2014 inhibits the activity of mTOR, which may result in the induction of tumor cell apoptosis and a decrease in tumor cell proliferation. mTOR is upregulated in a variety of tumors, plays an important role downstream in the PI3K/Akt/mTOR signaling pathway.