AZD-0156

• Catalog#: C-1045
• Targets: ATM
• Synonym: AZD0156; AZD-0156; AZD 0156

Technical Data

• Product Name: AZD-0156
• Chemical Formula: C26H31N5O3
• CAS#: 1821428-35-6
• Moleculer Weight: 461.56
• Appearance: Solid powder
• Purity: > 99% by HPLC
• Solubility: Soluble in DMSO
• Storage: Room temperature for months, or -20ºC for 3 years

Description

AVL-292 (Spebrutinib) is an orally bioavailable, selective inhibitor of BTK, with potential antineoplastic activity. Upon administration, AVL-292 targets and covalently binds to BTK, thereby preventing its activity. By irreversibly inhibiting BTK, administration of this agent may lead to an inhibition of B cell receptor (BCR) signaling and may inhibit cell proliferation of B-cell malignancies.