SKU: C-1044-5mg
 AVL-292 Chemical Formula: C22H22FN5O3, CAS#: 1202757-89-8, Molecule Weight: 423.44 , Appearance: Solid powder , Purity: > 99% by HPLC, Solubility: Soluble in DMSO
$69.99

  • Catalog#: C-1044
  • Targets: BTK
  • Synonym: CC292; CC-292; CC 292; AVL292; AVL-292; AVL 292

Technical Data

  • Product Name: AVL-292
  • Chemical Formula: C22H22FN5O3
  • CAS#: 1202757-89-8
  • Moleculer Weight: 423.44
  • Appearance: Solid powder
  • Purity: > 99% by HPLC
  • Solubility: Soluble in DMSO
  • Storage: Room temperature for months, or -20ºC for 3 years

Description


AVL-292 (Spebrutinib) is an orally bioavailable, selective inhibitor of BTK, with potential antineoplastic activity. Upon administration, AVL-292 targets and covalently binds to BTK, thereby preventing its activity. By irreversibly inhibiting BTK, administration of this agent may lead to an inhibition of B cell receptor (BCR) signaling and may inhibit cell proliferation of B-cell malignancies.