SKU: C-1041-5mg
AT13387 (Onalespib) Solid Powder
  • Catalog#: C-1041
  • Targets: Hsp90
  • Synonym: AT13387; AT-13387; AT 13387; Onalespib; Onalespib lactate

Technical Data

  • Product Name: AT13387 (Onalespib)
  • Chemical Formula: C24H31N3O3
  • CAS#: 912999-49-6 (free base)
  • Moleculer Weight: 409.23
  • Appearance: Solid powder
  • Purity: > 99% by HPLC
  • Solubility: Soluble in DMSO
  • Storage: Room temperature for months, or -20ºC for 3 years


AT13387 (Onalespib) is an orally bioavailable, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity. AT-13387 selectively binds to Hsp90, thereby inhibiting its chaperone function and promoting the degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival. Hsp90 regulates the folding, stability and degradation of many oncogenic signaling proteins.