SKU: C-1025-5mg
AMG-337 Soild Powder
$99.99
  • Catalog#: C-1025
  • Targets: c-MET
  • Synonym: AMG337; AMG-337; AMG 337

Technical Data

  • Product Name: AMG-337
  • Chemical Formula: n/a
  • Moleculer Weight: 473.38
  • CAS#: 1173699-31-4
  • Appearance: Solid powder
  • Purity: > 99% by HPLC
  • Solubility: Soluble in DMSO
  • Storage: Room temperature for months, or -20ºC for 3 years

Description


AMG-337 is an orally bioavailable inhibitor of the proto-oncogene c-Met with potential antineoplastic activity. AMG-337 selectively binds to c-Met, thereby disrupting c-Met signal transduction pathways. This may induce cell death in tumor cells overexpressing c-Met protein or expressing constitutively activated c-Met protein.