SKU: C-1017-5mg
AEE-788 liquid powder- labshops.com
$99.99
  • Catalog#: C-1017
  • Targets: EGFR
  • Synonym: AEE788, AEE 788, AEE-788

Technical Data

  • Product Name: AEE-788
  • Chemical Formula: C27H32N6
  • Moleculer Weight: 440.58
  • CAS#: 497839-62-0
  • Appearance: Solid powder
  • Purity: > 99% by HPLC
  • Solubility: Soluble in DMSO
  • Storage: Room temperature for months, or -20ºC for 3 years

Description


AEE-788 is an orally bioavailable multiple-receptor tyrosine kinase inhibitor. AEE788 inhibits phosphorylation of the tyrosine kinases of epidermal growth factor receptor (EGFR), human epidermal growth factor receptor 2 (HER2), and vascular endothelial growth factor receptor 2 (VEGF2). Upon administration, AEE-788 results in receptor inhibition, the inhibition of cellular proliferation, and induction of tumor cell and tumor-associated endothelial cell apoptosis.