ABT-888

• Targets: PARP
• Synonym: ABT888; ABT-888; ABT 888
• Chemical Name/IUPAC: (R)-2-(2-methylpyrrolidin-2-yl)-1H-benzo[d]imidazole-4-carboxamide
• SMILES Code: O=C(C1=C2C(NC([C@]3(C)NCCC3)=N2)=CC=C1)N

Technical Data

• Product Name: ABT-888
• Chemical Formula: C13H16N4O
• Moleculer Weight: 244.29
• CAS#: 912444-00-9 (free base)
• Appearance: Solid powder
• Purity: > 99% by HPLC
• Solubility: Soluble in DMSO
• Storage: Room temperature for months, or -20ºC for 3 years

Description
ABT-888 is a poly(ADP-ribose) polymerase (PARP) -1 and -2 inhibitor with chemosensitizing and antitumor activities.