ABT-888
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- C-1014
- Targets: PARP
- Synonym: ABT888; ABT-888; ABT 888
- Chemical Name/IUPAC: (R)-2-(2-methylpyrrolidin-2-yl)-1H-benzo[d]imidazole-4-carboxamide
- SMILES Code: O=C(C1=C2C(NC([C@]3(C)NCCC3)=N2)=CC=C1)N
Technical Data
- Product Name: ABT-888
- Chemical Formula: C13H16N4O
- Moleculer Weight: 244.29
- CAS#: 912444-00-9 (free base)
- Appearance: Solid powder
- Purity: > 99% by HPLC
- Solubility: Soluble in DMSO
- Storage: Room temperature for months, or -20ºC for 3 years
Description
ABT-888 is a poly(ADP-ribose) polymerase (PARP) -1 and -2 inhibitor with chemosensitizing and antitumor activities.