MEK-162 (ARRY-162)
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- Catalog#: C-1035
- Available in : 5mg, 10mg, 50mg, 100mg and more (contact us for bulk orders)
- Targets: MEK
- Synonym: MEK162; MEK-162; MEK 162; ARRY162; ARRY-162; ARRY 162; ARRY438162, Binimetinib
Technical Data
- Product Name: MEK-162 (ARRY-162)
- Chemical Formula: n/a
- CAS#: 606143-89-9
- Appearance: Solid powder
- Purity: > 99% by HPLC
- Solubility: Soluble in DMSO
- Storage: Room temperature for months, or -20ºC for 3 years
Description
MEK-162 (ARRY-162) is a potent, orally bioavailable and non-ATP competitive inhibitor of MEK1/2 (IC50 = 12 nM ) and cellular pERK (IC50 = 11 nM).